مقايسه تاثير دريافت و عدم دريافت غذا حين همودياليز بر عوارض جانبي زودرس آن

Comparison of the Effect of Food and Non-food Ingestion During Hemodialysis on Early Acute Side Effects of Hemodialysis

Background and purpose: Food ingestion during hemodialysis may aggravate early side effects of hemodialysis due to hemodynamic changes. Therefore, this study was carried out to investigate the effect of food and non-food ingestion during hemodialysis on its early symptoms. Methods and materials: This clinical trial was conducted on the research population of ESRD Patients; 31 cases were selected through convenient and purposeful sampling. They were NPO during hemodialysis first, and received one meal (containing 325 Kcal) one hour after the second hemodialysis started. Their blood pressure, intensity of nausea and vomiting immediately before and after hemodialysis, and every 30 minutes during hemodialysis were measured and recorded. The obtained data were analyzed in SPSS using paired and independent t-test, Pearson and Spearman correlation coefficients, Wilcoxon and McNemar tests. Results: Blood pressure reduced 6.1 ±4.1 mmHg 60 minutes after hemodialysis started but in non-food hemodialysis, the reduction was 1067± 2.57 mmHg, and the difference was significant. Also nausea intensity after food ingestion increase in 11 patients (35.5%), but it increased in 5 cases (16.1%) after non- food hemodialysis, and the difference was significant. Vomiting intensity after food ingestion increased in 8 cases (25.8%) and in 1 patient (302%) upon non-food hemodialysis, the difference of which was significant. Conclusion: Food ingestion during hemodialysis causes a decline in blood pressure, and increases the intensity of nausea and vomiting. Therefore, food ingestion during hemodialysis should be avoided.