تاثير مصرف نارنج در كاهش علايم باليني بزرگي خوش خيم غده پروستات (Benign prostatic hypertrophy)

A Study of The Effect of Sour Orange on Reduction Clinical Symptoms of BPH

Introduction: The prevalence of BPH among 5-10 year old men is about 50% and it reaches 90% in 80 year old ones. The use of the components of citrus fruits containing a group of vitamines (specially C), flavonoid and a type of polysaccharides as pectin which are effective in treatment of hyperplasia , allergy and viral infection. Materials and Methods: This is a clinical-trial study conducted on two groups, each with 30 samples (patients drinking 60 ml sour orange Juice/daily and those administering 1 prozacin tablet daily as used in classical treatment). Convenient sampling was performed for selection of patients in both groups. From the patients refering to the specialty clinic in Jahrom. The data were collected through a checklist consisting of two part of demographic information and AUA which measures the severity of prostatic symptoms. SPSS software was used to analyzed data. Results: Comparison of the AUA mean scores before and after having sour orange juice revealed that the difference was significant (before: 25.833±0.823, after: 2.833±0.248, p=0.000) However, the same comparison for the control groups mean scores before and after taking the above mentioned tablet revealed a non-significant difference (before: 26.666±0.717, after: 26.666±0.723, p=1.000). comparison of AUA mean scores of the case and control groups revealed that the difference was statistically significant (case group: 2.833±0.248 and control group: 26.666±0.723, p=0.000) Conclusion: Considering the finding of this study, citrus fruit can be effective in reducing the symptoms of prostate hypertorophy .