شماره ركورد :
420191
عنوان مقاله :
اثر عصاره آبي دانه Securigera Securidaca بر فعاليت آنزيم كاتالاز گلبول هاي قرمز در موش هاي صحرايي ديابتي تيپ 1 (عصاره Securigera Securidaca و فعاليت كاتالاز)
عنوان به زبان ديگر :
Effect of Aqueous Seed Extract of Securigera Securidaca on Erythrocytes Catalase Activity in Type 1 Diabetic Rats
پديد آورندگان :
روستازاده، اباذر نويسنده دانشگاه علوم پزشكي ايران Roostazadeh, A , فيروزراي، محسن نويسنده دانشگاه علوم پزشكي ايران Firooz rai, M , شعباني، محمد نويسنده دانشگاه علوم پزشكي ايران Shabani, M
اطلاعات موجودي :
فصلنامه سال 1386 شماره 4
رتبه نشريه :
علمي پژوهشي
تعداد صفحه :
5
از صفحه :
9
تا صفحه :
13
كليدواژه :
ديابت , استرس اكسيداتيو , آنتي اكسيداني , گنده تلخه , كاتالاز
چكيده لاتين :
Background and objective Complications in diabetes mellitus are associated with free radicals and oxidative stress. The human body prevents these complications through antioxidant defense mechanisms. The aim of the study was to investigate the effect of aqueous seed extract of Securigera Securidaca on erythrocyte catalase activity in type1 diabetic rats. Methods At the present interventional study thirty male wistar rats were used. Animals were divided to two groups including normal and diabetic (n=15 per each group).Each group was divided further to control and experimental subgroups. The experimental subgroups were received 100 and 200 mg/kg/day of the plant extract intraperitoneally. After thirty days administration blood sample was directly collected from the heart and erythrocyte catalase activity was assessed. Results catalase activity decreased in diabetic control group significantly (P=0.002).Furthermore catalase activity in groups treated at two doses of 100mg/kg and 200mg/kg was significantly different as compared to control group(P=0.003). Conclusion The aqueous seed extract of Securigera Securidaca probably could be effective in decreasing diabetic complications through improvement of antioxidant response by altering catalase activity and consequently reducing oxidative stress.
سال انتشار :
1386
عنوان نشريه :
مجله دانشگاه علوم پزشكي قم
عنوان نشريه :
مجله دانشگاه علوم پزشكي قم
اطلاعات موجودي :
فصلنامه با شماره پیاپی 4 سال 1386
كلمات كليدي :
#تست#آزمون###امتحان
لينک به اين مدرک :
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