علائم، عوارض و بيماري زمينه اي همراه با زونا در بيماران بستري در بيمارستان الزهرا اصفهان 1385-1375

Manifestations , Complication and Underlying Disease Associated with Zona in the Al-Zahra Hospital of Isfahan (1375-1385).

Introduction: Zona is a disease due to reactivation of dormant Herpes Zoster virus in dorsal root gangelion and almost manifest by vesicular rash in one dermatom. Materials and Methods: 100 patients with a descriptive study, identified as having zona during ten years (1375-85) at Al-Zahra hospital in Isfahan were reviewed. Patients investigated from the point of age, sex prevalence, underlying disease involved and dermatom. Results: 1% of patients were under 20 years, %16 between 20 and 50 years and %83 greater than 50 years old . %45 of Cases were male and %55 were femle. Mean age of them were 61.4 ±2. Among 100 patients 68 cases had underlying disease. 23 cases had history of surgery in 2 resent months (%52.2 male), 15 cases had diabet type II (%46.7 male). 13 cases had malignancy (%69.2 male), 13 cases had used corticostroid (%46.2% male) and 4 cases had psychological disorder that all were female. The most involved dermatom in the patients were 34 trigeminal, 24 thoracic, 7 cervical, 16 lumber , 12 sacral and 7 Generalized. There were significantly relation between underlying disease and involved dermatom (P0.001), all of the patients with generalized dermatom were immunocompromised. Conclusion: Zona is more common and sever in immune compromised patients and people suffering from underlying disease. Therefore this matter necessitates prevention of disseminated forms and complication of disease through increasing awareness of patients in this regard and earlier presentation for treatment.