بررسي مقاومت دارويي شيگلاهاي جدا شده از بيماران مبتلا به اسهال شيگلايي مراجعه كننده به بيمارستان 22 بهمن شهر گناباد

The study of antimicrobial resistance of shigella strains isolated from diarrheal patients in Gonabadʹs 22-Bahman hospital, 2005-2006

Background and Aim: In this study drug susceptibility of shigella strains was detected in diarrheal patients in Gonabadʹs 22-Bahman hospital, 2005-2006. Materials and Methods:For this purpose, Kirby-Bauer method of susceptibility testing was used for drug susceptibility of shigella strains. Results: In total, 134 samples belong to the patients referred to Gonabad s 22-Bahman hospital, were collected. From 134 cases, 32 cases were identified as shigellosis. All of the isolates were sensitive to Cefotaxime, Ceftizoxime and Ciprofloxacin, 81/3% and 53/1% of the isolates were resistant to Tetracycline and Sulfametoxazole -Trimetoprime respectively. Conclusion: The dramatic rise in resistance has a major implication for the appropriate selection of antibiotics and brought empiric use of Tetracycline and Sulfametoxazole- Trimetoprime in to question.