ارتباط سن، جنس و موقعيت آناتوميك كليه اهداكنندگان با ميزان بقاي گرافت در گيرندگان پيوند

Association between renal graft survival and age, sex and anatomical position

Background: Renal transplantation is the treatment of choice for patients with end stage renal disease (ESRD). The present study was designed to evaluate the association between renal graft survival and age, sex and anatomical position. Materials and methods: For this historical cohort study, 129 patients who have received renal transplantation during a 5-year period (1998-2003) in Modarres Hospital in Tehran were included through a non probability sampling. The creatinine level one year following the transplantation was considered for graft outcome. Meanwhile, graft rejection, death, transfusion and hypertension before and after transplantation have been evaluated. Results: Renal transplantation was successfully achieved in 79.8% of cases. Reduction in blood pressure following the transplantation and transfusion was not significantly differed between the female and male, left- and right-kidney, and older and younger than 28 years old recipients. The minimum rejection rate was observed in male-to-female group; however, the minimum mortality rate was reported in female-to-female group. Decreased serum creatinine level was appeared earlier in the transplantʹs recipients of left-kidney and female subjects. Conclusion: We suggest longer follow up of blood pressure and kidney transplantation from donor with brain death to improve renal graft survival.