ساخت نانورتاكسن‌هاي سيكلودكسترين با پلي اتيلن گليكول و كاربردهاي نانورتاكسن‌ها

Nanorotaxanes of Cyclodextrin with Poly(Ethylene Glycol) and their Applications

Cyclodextrins are a family of cyclic oligosaccharides composed of_-(1,4) linked glucopyranose subunits. Cyclodextrins are useful molecular chelating agents. These compounds having supramolecular structures carry out chemical reactions that involve intramolecular interactions where covalent bonds are not formed between interacting molecules, ions or radicals. The majority of all these reactions are of ʹhost-guestʹ type.. Because of their inclusion complex forming capability, the properties of the materials with which they complex can be modified significantly cyclodextrins are most important, . As a result of molecular complexation phenomena CDs are widely used in many industrial products, technologies and analytical methods. The negligible cytotoxic effects of CDs are an important attribute in applications such as rug carrier, food and flavours, cosmetics, packing, textiles, separation processes, environment protection, fermentation and catalysis. Poly(ethylene glycol) forms inclusion compounds with a , f and y -cyclodextrins. The inclusion compounds are in microfibres , arranged in a columnar microstructures in the crystal lattice. The inclusion compound may form needles < prisms or hexagonal crystals from crystallization in a phosphate buffers under sonic energy.