اپيدميولوژي تومورهاي غدد بزاقي در يك بررسي ده ساله دربيمارستان لقمان

A ten years epidemiologic study of salivary gland tumors in Loghman Hospital

Background and Aim: Salivary gland tumors are rarely reported comprising 2-3% of head and neck neoplasms. About 75% of salivary gland tumors are benign and 25% are malignant. Major salivary glands include parotid, submandibular and sublingual while minor salivary glands distribute through submucosa of palate, lip and buccal mucosa. The present study was done to evaluate salivary gland tumors in patients referred to Loghman hospital during 1997-2007. X. , X Materials & Methods: In this retrospective descriptive study, patients with salivary gland tumors were studied by means of existing data technique. Data collection sheet included gender, age, location and size of tumor, clinical and pathologic diagnosis, pathological diagnosis and treatment. The histopathological analysis of all cases was meticulously reviewed and classified by 3 expert pathologists. Descriptive analysis was used for the analysis. Results: Forty four patients were found with salivary gland tumors. 36.4% of them were females and 63.6% were males. Benign tumors calculated about 72.7% and malignant tumors as 27.3%. The most common tumors were pleomorphic adenoma (70.4%), warthin tumors (2.2%), and mucoepidermoid carcinoma (11.3%) was the most common malignancies. Parotid (77.2%) was the most common site following by submandibular gland (11.3%) and palate with 11.3% occurrence. The size range of tumors was 1-9 cm with the average size of 2-4cm. Conclusion: Pleomorphic adenoma was the most common benign tumor and mucoepidermoid carcinoma was the most malignant tumor resembling the other studies done in the field.