بررسي كاهش امكان سرطان با استفاده از چند سويه باكتري هاي پروبيوتيك در مقابل برخي از مواد كارسينوژن

Decreased risk of cancers and some carcinogenic factors by probiotic cultures

Background: Chemical carcinogens may be produced by metabolic activity of microbes residing in gastrointestinal system. Researches suggest that the consumption of probiotic cultures may decrease the risk of cancer. The aim of this study was to evaluate inhibitory effects of probiotic cultures on mutant and cancerous cells. Materials and methods: In this experimental study, antimutagenic effects of probiotic cultures, including Bifidobacterium bifidus, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus rhamnosus and Streptococcus thermophilic, were assessed by the Salmonella/ microsome assay upon sodium azid and nitrosamine by Ames test. Results: There were anticancer and antimutagenic activities of probiotic cultures. Anticarcinogenic effects of probiotic cultures were mostly above 40%, representing their potent anticarcinogenic activities. Conclusion: This study showed that probiotic cultures have potent anticarcinogenic and antimutagenic activities.