كليدواژه :
ناقلين بيني , استافيلوكوك آريوس , پرسنل بيمارستان , مقاومت آنتي بيوتيكي
چكيده لاتين :
Background and Objectives: Staphylococcus aureus carriers are among the important causes of nosocomial
infections. According to the studies, medical and health workers have always been considered as a source of
nosocomial infections. The aim of this study is determination of the prevalence of the nasal carriers of
staphylococcus aureus and antibiotic resistance in clinical wardsʹ staffs in Ali- Ebne Abitaleb hospital, in
Rafsanjan.
Material and Methods: This cross- sectional study was done in clinical wards staffs, of Ali- Ebne Abitaleb
hospital. Two handred and twenty people between 22 and 58 years old were studied. Sampels were obtained by
sterile swabs from deep tissue of anterior nares and then cultured. For identification of staphylococcus aureus,
the major tests of catalase, coagolase and DNase were done. Disks of penicillin, cefixim, vancomycin, oxacillin,
erythromycin, clindamycin, cefazolin, nitrofurantion, co- trimoxozole, ciprofloxacin, cephalothin doxycyclin and
methicillin were used for antibiogram. Data were analyzed using SPSS. Chi- Square and T tests were used where
appropriate.
Results: Among the 220 staffs who were studied, 44(20%) were nasal carriers of staphylococcus aureus.
Resistance to antibiotics were as follows: penicillin (100%), cefixim(100%), methicillin (97.7%), oxacillin
(77.3%) erythromycin (11.4%), doxycyclin (9.1%), cephalotin (6.9%), ciprofloxacin (6.8%), co- trimoxozole
(4.5%), clindamycin (2.3%), cefazolin (2.3%) and nitrofurantoin and vancomycin(sensitive).
Conclusion: Considering the remarkable number of nasal carriers of staphylococcus aureus, and specially the
high resistance to methicillin, oxacillin and penicillin among hospital staff, in order to prevent nosocomial
infections we suggest that the carriers among the staff should be identified and treated properly.