فراواني هپاتيت A و E در پرسنل نظامي

Hepatitis A and E in Militaries

Background and objective: Hepatitis viruses of fecal-oral origin are responsible for a high morbidity and mortality throughout the world. Hepatitis A (VHA) and hepatitis E (VHE) are at present the cause of severe viral hepatitis of enteric origin. Water is the principle vector in the spread of these viruses. Aim of this study was evaluation of HAV and HEV immunity in adult. Materials and methods: This study is a cross-sectional that conducted in eight- hundred of military persons in capital city of Iran in 2006.Five ml of blood sample was taken from each person and tested at the laboratory of Baqiyatallah University for anti-HEV IgG and IgM antibody by enzyme immunometric assay (Diapro, Italy HEV EIA) and ELSIA test for anti hepatitis A virus IgG and IgM antibody with broad test of Abbott-HAV AB META-AXSYM system. Data were analyzed with SPSS 13 program of computer and T test, man Whitney and Chi-square were used for statistical analysis. Results: All persons were man and mean age 19±1SD. In here781 (97.7%) person had anti hepatitis A virus IgG antibody and only 9 (1. 1%) had HEV IgG positive. All persons had negative HEV and HAV IgM antibody Past history of hepatitis was negative in all persons. Demographic information had not significant related with anti hepatitis A and E virus antibody. Conclusion: Enteric viral hepatitis and its complications threat the adult and military personnel. This study suggest that up than 97.7% of persons were immune to HAV but 98%) of them non immune to HEV, therefore at this time vaccination for hepatitis A virus wasnʹt require for adult in Iran. But Prevention of HEV infection is important for them and until effective vaccine was found, in time that they traveled to low sanitation areas should engage in practices and educated to avoiding drinking water of unknown purity.