شيوع عفونت هاي ادراري در معلولين با ضايعات نخاعي و تعيين حساسيت دارويي ايزوله هاي جداشده

Urinary Tract Infections in the Injuries with Spinal Disorders

Background and Objectives: Urinary tract infections are one of the most common infections around the world. Frequently injuries with spinal disorders are encountered with UTIs. Widespread use of antimicrobial agents has resulted in an increasing incidence of resistance in bacteria all over the world. Hence, the investigation on bacterial resistance is necessary to evaluate the rate of antimicrobial resistance among bacteria isolated from UTIs in that population. Material and methods: Two hundred clinical bacterial isolates were collected by urine cultures from injuries with spinal disorders and identified by standard methods according to NCCLS guidelines. Then antimicrobial susceptibility testing was determined by disk agar diffusion method. Results: The percentage of bacterial strains isolated from patients were Proteus spp.25.6%, Klebsiella spp. 23%, E. coli 17%, Pseudomonas 14.5%, Entrobacter spp. 8.5%, Citrobacter spp. 3%, Staphylococcus spp. 105%, Serratia spp. 1.5%, Hafnia spp. 0.5%, and Morganella 0.5%. The most of bacterial strains isolated from UTIs were resistant to different antibiotics. Approximately more than 50% of bacterial isolates showed resistance to more than 75% of antimicrobial agents. Furthermore, Pseudomonas spp. showed a high rate of resistance against commonly used antimicrobial agents. Conclusion: This study represents high level of antibiotic resistant of bacterial strains isolated from UTI patients against different antimicrobial agents. It is because of inappropriate and incorrect administration of antimicrobial agents in blind cases. This problem remarks significance of performing antimicrobial susceptibility testing before empiric antibiotic therapy. To overcome this problem use of unnecessary antibiotics therapy should be limited.