شماره ركورد :
440762
عنوان مقاله :
شناسايي عوامل موثر بر بقاي بيماران مبتلا به سرطان هاي كولون و ركتال مراجعه كننده به مركز تحقيقات گوارش دانشگاه علوم پزشكي شهيد بهشتي: تحليل بقاي پارامتري بر اساس الگوي زمان شكست شتابنده با تصحيح شكنندگي
عنوان به زبان ديگر :
Recognition of the factors affecting survival in colon and rectal cancer patients referred to RCGLD center of Shahid Beheshti University of Medical Sciences: accelerated failure time parametric survival analysis with frailty
پديد آورندگان :
اصغري جعفرآبادي، محمد نويسنده دانشكده بهداشت,دانشگاه علوم پزشكي تبريز,تبريز,ايران Asghari jafarabadi , Mohamad
اطلاعات موجودي :
فصلنامه سال 1389
رتبه نشريه :
علمي پژوهشي
تعداد صفحه :
14
از صفحه :
51
تا صفحه :
64
كليدواژه :
بقا , الگوي زمان شكست شتابنده , ركتوم , شكنندگي , كولون
چكيده لاتين :
Background and aim: Different diagnostic factors of colon and rectal cancer (CRC) affect the survival of patients, prognosis and consequently treatment application. The rate of colorectal cancer is being increased in Iran, especially in younger ages, made it more valuable to study this type of cancer. However, evaluation of the risk factors of the cancer as a whole would not provide thorough understanding of the cancer. Therefore, the aim of this study was to determine specific risk factors affecting colon and rectum cancers Methods: A total of 1219 patients with CRC diagnosis, according to the pathology report of cancer registry of RCGLD from 1 January 2002 to 1 October 2007, were entered into the study. Data were analyzed using univariate and multivariate Accelerated Failure Time (AFT) parametric survival model with frailty, utilizing STATA statistical software. Results: Based on the results of this analysis, for colon cancer, females, patients without inflammatory bowel disease (IBD), patients with poorly differentiated tumor grade and patients pathologic with stage of I had higher survival probability. For these patients, there was not any correlation between history of alchol consumption and the size tumor. In the rectal cancer, patients with surgery as the kind of first treatment used, ʹhad higher survival probability. For these patients personal history and pathologic stage werenʹt statistically significant. In addition, in both types of cancers, 25-29.9 and over than 30 categories of body mass index (BMI) had higher survival probability, respectively and patients with BMI less than 18.5 had lower survival probability. In general, the survival rate in rectal cancer patients was higher than those with colon cancer. Conclusions: Site-specific evaluation of colon and rectum can lead to a deeper understanding of factors affecting these cancers. It may help design the clinical trials, better diagnosis of diseases and optimal administration of specific treatments.
سال انتشار :
1389
عنوان نشريه :
مجله دانشگاه علوم پزشكي شهركرد
عنوان نشريه :
مجله دانشگاه علوم پزشكي شهركرد
اطلاعات موجودي :
فصلنامه با شماره پیاپی سال 1389
كلمات كليدي :
#تست#آزمون###امتحان
لينک به اين مدرک :
بازگشت