چكيده لاتين :
Background and aim: Urinary tract infection (UTI) is a common and serious clinical problem in newborns. Previous studies have suggested that jaundice may be one of the signs of a UTI in infants. The aim of this study was to evaluate the incidence, age presentation, severity of jaundice, signs and complications of UTI in newborns with asymptomatic, unexplained .indirect hyperbilirubinemia in the first month of life Methods: This case-control study was conducted at the Neonatal intensive care unit, Ghaem Hospital, in Mashhad from May 2004 to April 2009. We . jaundiced infants for the evidence of having UTI,evaluated asymptomatic Some laboratory tests such as a serum fractionated bilirubin level, as well as urinanalysis and a urine culture were performed in all patients. Renal ultrasound was performed in almost all the cases with UTI. Detailed prenatal, ,questionnaires, which were included demographic information intrapartum, postnatal events and risk factors were filled. The control group
was jaundiced- infants with unknown etiology. Results: A total of 1487 patients were enrolled in this study. From these patients 1061 infants were evaluated for UTI. There was a statistically significant difference (P<0.05) between the two groups regarding age presentation, age admitted to hospital, age improved jaundice, serum bilirubin level and hospital stay. UTI was diagnosed in seventy four (6.97%). Renal ultrasound showed urinary tract abnormalities in thirty two (32%) patients. Six infants had unilateral grade 1-3 reflux in voiding
Corresponding author:
Neonatal research center, pediatric Dept., Mashhad Univ. of Med. Sci. Mashhad, Iran Tel:
0985118412069- Email
BoskabadiH@mums.ac.ir
cystourethrogram.
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,Conclusion: In our study UTI was found in 7% of asymptomatic we recommend that a UTI test should be jaundiced infants. Therefore included in asymptomatic, jaundiced infants presenting after five day of These infants should be evaluated for urinary .life as part of their evaluation tract abnormalities by renal ultrasound and voiding cystourethrogram.