بررسي فعاليت ضدميكروبي عصاره هاي ميوه و هسته خرما (Phoenix dactylifera L) عليه سويه هاي استافيلوكوكوس اوريوس مقاوم

Evaluation of the Antibacterial Activity of the Extracts of Date Palm (Phoenix dactylifera L,) Fruits and Pits on Multi-Resistant Staphylococcus aureus

Introduction: This study was designed to evaluate and determine the antibacterial activity of date palm {Phoenix dactylifera L.) fruit and pit against multidrug-resistant staphylococcus aureus. Materials and Methods: Date fruits were obtained from a local date market in Iran. The pits were separated from the flesh and their ethanol and acetone extracts were prepared. Fifty six strains of Staphylococcus aureus were isolated from nosopharyngial of hospitalized patients. The antibiotical resistance of the extracts was determined using Kirby-Bauer method. Twelve multidrug-resistant of these strains were selected and antibacterial activities of the extracts were evaluated by disc-diffusion method. Results: The results showed that the extracts of date fruit did not have antibacterial activity against the bacteria tested, but the pit extracts affected some of the isolated strains. The acetone extract of pits had higher inhibition effect than their ethanolic extract. Conclusion: This study indicated that date palm pit extract, had an antibacterial activity against tested microorganisms and we can support the idea of proposing the use of this substance as a natural antibacterial agent in treatment of infected wounds and other diseases.