بررسي آلودگي به توكسوپلاسما در بيماران بدخيم سرطاني بروش الايزا و مقايسه آن با گروه كنترل در شهرستان تبريز (1386)

Survey of Toxoplasma contamination in malignant canceric patients by ELISA method and comparison it with control group in Tabriz (1386)

Toxoplasmosis is a common zoonotic infection between human and animal in the world. In the congenital form pathogenic agent is transmitting to the fetus through the maternal placenta. Acquired infection is due to ingestion of the oocysts, which are exfacted by cats or transmitted through the contaminated meat. Congenital infection can lead to fetal death, pathological changes of CNS or the eye diseases. The acquired form of the disease often is no sign, or is characterizes by general lethargy, swallow of lymphatic nodes and chorioretinitis. In the compromised patients or the patients with malignancy or tissue plants, lethal and acute infections take place. The aim of this study was the investigation of prevalence of antibody of anti toxoplasma gondii in the serum of malignant patients referred to the Tabriz Ghazi and Imam Hospitals. In this cross-sectional survey, a number of 150 blood sample of the malignant and a number of 150 blood samples of the control patients were collected and were tested (IgG and IgM) by the ELISA method. Results showed that total prevalence of Anti toxoplaxma IgG malignant patients was 40.66X. The high infection rate was between age group of upper 70 (66.66X) and the least rate was seen in the age group of 21-30 (26.92X). Also in control group the same condition was considered. So, according to the high positive cases among the malignant patients, there should be some regular screen programs to recognize the chronic infection which are going to the acute. The measurement of the serai titration of these patients should be done and undergone the antiparasitic treatments. Vet.J.of Islamic.Azad.Univ., Garmsar Branch. 5,1:53-59,2009.