بررسي آلودگي به توكسوپلاسما در بيماران پيوندي كليه بروش الايزا و مقايسه آن با گروه كنترل در شهرستان تبريز (1386)

Survey of Toxoplasma contamination in kidney recipient patients by ELISA method and comparison it with control group in Tabriz (1386)

Toxoplasmosis is a common zoonotic infection between human and animal in the world. In the congenital form pathogenic agent is transmitting to the fetus through the maternal placenta. Acquired infection is due to ingestion of the oocysts, which are exfacted by cats or transmitted through the contaminated meat. Congenital infection can lead to fetal death, pathological changes of CNS or the eye diseases. The acquired form of the disease often is no sign, or is characterizes by general lethargy, swallow of lymphatic nodes and chorioretinitis. In the compromised patients or the patients with malignancy or tissue plants, lethal and acute infections take place. The aim of this study was the investigation of prevalence of antibody of anti toxoplasma gondii in the serum of kidney recipient patients referred to the Tabriz kidney and Imam Hospitals. In this cross-sectional survey, a number of 96 blood sample of the kidney recipient and a number of 96 blood samples of the control patients were collected and were tested (IgG and IgM) by the ELISA method. Results showed that total prervalence of Anti toxoplaxma IgG in kidney recipient patients was 36.46%. The high infection rate was between age group of 41-50 (60%) and the least rate was seen in the age group of 31-40 (16%). Also in control group the same condition was considered. So, according to the high positive cases among the implantic patients, there should be some regular screen programs to recognize the chronic infection which are going to the acute. The measurement of the serai titration of these patients should be done and undergone the antiparasitic treatments. Vet.J.ofIslamic.Azad.Univ., Garmsar Branch. 3,4:173-179,2007.