مقايسه تأثير تزريق ليدوكايين 2 درصد داخل كاف لوله تراشه و بوپيواكايين 25/. درصد در كاهش سه عارضه لوله گذاري داخل تراشه (سرفه، زور زدن و لارنگواسپاسم) هنگام برگشت بيماران تحت بيهوشي عمومي به حالت هوشياري

Comparising Effects of Lidocaine 2% and Bupivacaine 0/25% Infiltrating into Endotracheal Tubeʹs Cuff in order to Reduce in Occurance of Cough, bucking and Laryngospasm During Emergence from Anesthesia

Background: Cough, bucking and laryngospasm during emergence from anesthesia are side effects of endotracheal intubation and associate with increased in intracranial pressure and ischemia of myocardium. We compared effects of Lidocaine 2% and Bupivacaine 0/25% infiltrating into endotracheal tubeʹs cuff in order to reduce in occurance of cough, bucking and laryngospasm during emergence from anesthesia. Methods: 95 adult patients (49 in lidocaine group and 46 in bupivacaine group) undergoing elective surgery under general anesthesia in Tabriz Zakarya hospital in 2009-2010 enrolled in a double blind randomized clinical trial. Occurance of cough, bucking and laryngospasm during emergence from anesthesia noted and analyzed with SPSS16 with independent-t test. Results: There was no significant difference between lidocaine 2% and bupivacaine 0/25% in reducing occurance of cough, bucking and laryngospasm (appending on duration of surgery) during emergence from anesthesia. Conclusion: Considering important side effects of bupivacaine, such as neurologic and cardiovascular side effects, we do not recommend using bupivacaine 0.25% instead of lidocaine 2% to infiltrate into endotracheal tubeʹs cuff in order to reduce occurance of cough, bucking and laryngospasm during emergence from anesthesia.