اثر عصاره كومبوچا بر چاقي و ميزان چربي انباشته شده احشايي در موش هاي Rat نر بالغ نژاد Wistar

The effect of Kombucha extract on obesity and the rate of fat accumulation in visceral mass of male Wistar Rat.

Introduction: Obesity and increase of body weight are major problems in developed and developing countries and they are the most important cause of atherosclerosis, cardiac and blood vessels diseases. The purpose of this study was to investigate the effect of kombucha extract on the rate of compact visceral lipid and body weight and triglyceride in male Wistar rats. Methods: Animals were divided in 4 groups: 1) Control group which received water and food diet. 2) Sham group which received water and high fat diet (included: 66.5g Carbohydrate, 20.lg Fat, and 4.49g protein). 3) Experimental group 1 received high fat diet and kombucha extract. 4) Experimental group 2, received food diet and kombucha extract. The duration of the treatment continued for 8 weeks. After weighting, the animals were anesthetized with ether. After treatment (8weeks), blood serum was prepared and amount of triglyceride was measured, and the weight compact lipid in their body was collected and their weight was determined. Findings: The results showed that the weight of animals after the treatment period was decreased (p<0.05). On the other hand, the weight of visceral lipid in both experimental groups as compared with control group was significantly decreased (p<0.001). On the other hand, serum level of TG in both experimental groups were showed significant decrease as compared with control group (p<0.001). Conclusion: using of the kombucha extract can cause losing weight, and decrease lipid storage and also decrease triglyceride. Thus probably this extract could be used in treating diseases such as obesity and cardiac and blood vessel diseases. Keywords: Kombucha, Obesity, Triglyceride, rat.