نقش سيستم آدرنرژيك در تاثير ميدان الكترومغناطيس بر احساس درد حاد

The role of adrenergic system on the effect of EMF on acute pain sensation

Although numerous factors participate in pain sensation, efficient studies have never been performed on these factors yet. Among these factors modifying effects of Electro Magnetic Field (EMF) on both intensity and duration of pain sensation is undeniable.This study has been performed on ten quintet groups of mice. In fact, the role of adrenergic system on the effect of EMF on acute pain sensation has been examined treating with four drugs (yohimbine, xylazine, propranolol and salbutamol). The animals were divided into two groups, the first group were exposed to EMF (one hour in a day for 7 days), whereas the second group did not. Both groups were treated with the drugs (IP) separately. The results revealed that Yohimbin (a2 Blocker) decreased and Xylazine (a2 Agonist) increased the analgesic effect of EMF on acute pain but Propranolol (pi, P2, 03 Blocker) and Salbutamol (P2 Agonist) didnʹt show any significant difference in analgesic effect of EMF on acute pain.In conclusion, the results showed that the EMF has the antinociceptive effect on the acute pain threshold via adrenergic system.