تشخيص و درمان تحت فشار بودن نخاع ناشي از هماتوپوئز خارج مغز استخوان در يك بيمار مبتلا به تالاسمي اينترمديا

Diagnosis and Treatment of Spinal Cord Compression Secondary to Epidural Extramedullar Hematopoiesis in A Patient with Thalassemia Intermedia

Extramedullary hematopoiesis (EMH) is a rare disorder, characterized by the appearance of the hematopoietic elements outside of the bone marrow, which occurs in patients with chronic myeloproliferative disorders or congenital hemolytic anemias. We report a case with a diagnosis of thalassemia intermediate, EMH in spinal cord and paravertebral mass. A 20-yr-old female who initially presented with back pain and leg weakness was found to have paravertebral mass in the spinal cord. We attempt to report and treat this rare case, in which EMH was diagnosed. In conclusion, based on characteristic radiographic findings and bone marrow scanning with technetium 99M sulfur colloid, it is important to recognize spinal cord extramedullary hematopoiesis as a differential diagnosis of epidural masses. In geographical areas where thalassemia is prevalent, to avoid unnecessary surgical interventions, spinal cord extramedullary hematopoiesis should be considered in differential diagnosis of patients who have chronic anemia.