تاثير تركيبات جايگزين آنتي بيوتيك بر پاسخ ايمني همورال و برخي فراسنجه هاي سرم خون جوجه هاي گوشتي

Efficiency evaluation of antibiotic growth promoterʹs alternatives on immune response and some blood metabolites in broiler chickens

A study was conducted to evaluate efficiency of antibiotic growth promotersʹ alternatives on immune response and on concentrations of some blood parameters using 360, 1-d-old male broiler chickens (Ross 308) in a randomized complete block design. Six experimental groups were: 1- Control (basal diet without antibiotic or antibiotic alternatives), 2- Antibiotic (Virginamycin, 15 PPM), 3- Probiotic (Protexin, 0.1 g/kg), 4- Prebiotic (mannan-oligosaccharide, Immnowall- 0.1 g/kg), 5- Medicinal Plants (Digestarom, 0.45 g/kg) and 6- Organic acids (Formycine Gold PX, 0.4 g/kg). Antibody production against sheep red blood cells was increased by diet supplementation of growth promoter antibiotic alternatives in diets (P<0.05). Antibiotic alternatives applied in present study significantly reduced the cholesterol, triglyceride and LDL concentrations of blood serum (P<0.05), while serum HDL levels remained unaffected (P>0.05). Concentration of hepatic enzymes in blood serum of chickens fed diets containing growth promoter antibiotic alternatives, reduced compared to control and antibiotic groups. Antibiotic growth promoterʹs alternatives used in this study improved the immune system and liver performances in broiler chickens, as these additives can reduce cholesterol levels of blood serum.