Antibiotic Resistance in Escherichia Coli Strains Isolated from Urine of Inpatients and Outpatients

T he urinary tract infections regarded as a health problem around the world and not only as an agent of nosocomial infections but also infections in the community. Community acquired UTIs cause significant illness in the first 2 years of life [1]. Urinary tract infections in both inpatient and outpatient are common and widespread use of antibiotics is often the cause of emerging one or more antibiotic-resistant microorganisms [2]. Most studies have shown higher antibiotic resistance in bacterial strains isolated from hospitalized patients than outpatients. In this study, antibiogram was performed using disk diffusion susceptibility method according to NCCLS standards of the International Committee [3]. 8 different antibiotics, including ciprofloxacin (CP: 30 ?g), ceftriaxone (CRO: 30 ?g), cephalotin (CF: 30 ?g), cefixime (CFM: 5 ?g), cotrimoxazole (SXT), nalidixic acid (NA: 30 ?g), nitrofurantoin (FM: 300 ?g), gentamicin (GM: 10 ?g) were used for antibiogram. During 1388 the total number of urine samples sent to hospital microbiology laboratories valiasr (aj) of Arak was 5156, of which 446 samples (65.8%) were positive for E. coli culture.