فراواني آلوپسي آندروژنيك در ديابت نوع 2 در مقايسه با افراد سالم شهر اصفهان: گزارش كوتاه

Comparison of androgenic alopecia distribution among type 2 diabetes and healthy women in Isfahan city: a brief report

زمينه و هدف: مقاومت به انسولين از جمله ريسك فاكتورهای مهم ديابت می‌باشد. مقاومت به انسولين می‌تواند با آلوپسی آندروژنيك نيز مرتبط باشد. مطالعه حاضر جهت بررسی رابطه بين آلوپسی آندروژنيك و ديابت نوع 2 انجام گرديد. روش بررسی: در يك مطالعه تحليلی از نوع مورد- شاهدی، گروه مورد از زنان مبتلا به ديابت نوع 2 و گروه شاهد از زنان غيرديابتی مراجعه‌كننده به درمانگاه‌های بيمارستان‌های الزهرا، نور و امين اصفهان در سال 1390 انتخاب شدند. حجم نمونه در گروه مورد و شاهد 141 نفر برآورد شد. يافته‌ها: ميانگين سنی و نمايه توده بدنی در افراد شركت كننده در مطالعه به ترتيب 8/12±96/58 سال و kg/m2 25/6±4/15 بود. ارتباط معناداری بين ديابت مليتوس نوع 2 و آلوپسی آندروژنيك ديده نشد (05/0

Background: Insulin resistant is important risk factors of diabetes and leads to development of chronic diseases such as diabetes and cardiovascular disease. Recent studies showed association between androgenic alopecia and insulin resistant. However, findings are controversial. Alopecia in women is a common heritable hair loss in central part of head. Aim of this study was investigation of androgenic alopecia distribution in type II diabetes and healthy women and hypothesis testing of relationship between diabetes and androgenic alopecia. Methods: This is a case-control study. Case and control groups were selected from type II diabetes and healthy women respectively that were refered to clinics of Alzahra, Noor and Amin Hospitals in Isfahan City, Iran in 2011. Participants were selected based on random sampling. Sample size was estimated 141 subjects in each group. Participants were visited by doctor and severity of androgenic alopecia was determined based on Ludwish criteria. Data were analyzed with SPSS software and 2 test. P<0.05 was considered as significant. Results: Mean age and body mass index were 58.96±12.8 year and 25.6±4.15 kg/m2 respectively in whole population. Findings not show any significant association between type II diabetes and androgenic alopecia (P<0.05). Comparison of distribution of alopecia severity according to Ludwish criteria separately showed similar result. In addition to, there was not any significant relationship between diabetes and alopecia after adjusting with body mass index as confounding factor (P<0.05). Conclusion: In the present study, there was not any significant relationship between type II diabetes and androgenic alopecia among diabetes and healthy women. However, more researches need to investigate this relationship in both gender and assess insulin resistant indices as homeostasis model assessment-estimated insulin resistance and androgenic alopecia.