پديد آورندگان :
Rasti، Mojtaba نويسنده M.Sc. of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran. , , Samarbafzadeh، Alireza نويسنده Associated Professor of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran. , , Neisi، Niloofar نويسنده Ph.D. Student of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center and Research Institute for Infectious Diseases of Digestive System, Deptartment of Virology, Faculty of Medicine, Jundishapur , , Makvandi، Manoochehr نويسنده Professor of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center and Research Institute for Infectious Diseases of Digestive System, Deptartment of Virology, Faculty of Medicine, Jundishapur , , Najafifard، Saeed نويسنده M.Sc. of Virology, Health Research Institute, Infectious and Tropical Diseases Research Center, Department of Virology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran. , , Sharifat، Moosa نويسنده B.Sc. of Laboratory Sciences, Department of Pharmacology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran. , , Zargar، Mahvash نويسنده Assistant Professor of Obstetrics and gynaecology, Department of Obstetrics and Gynaecology, Imam Khomeini Hospital, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. ,
چكيده فارسي :
Background: Regarding to fecal- oral transmission of hepatitis
E virus and risk of fulminant hepatitis in the third trimester of
pregnancy, the aim of the present study was to determine
seroprevalence of HEV in pregnant women with regard to age,
level of education, trimester of pregnancy and residency.
Material and methods: A total of 418 serum samples were
collected from January 2010 to January 2011. All pregnant
women filled out the questionnaire form. Serum samples were
examined for anti-HEV IgG and anti- HEV IgM using ELISA
method.
Results: From 418 women, 22 cases were positive for anti-
HEV IgG (5.26%) and in one woman (0.23%) anti- HEV IgM
was positive. In the age groups of 30-40 and 20-30 years, the
seropositivity for anti-HEV IgG was 8.6% and 2.5%,
respectively. In group with higher age the positive cases of anti-
HEV IgG was higher than in the other group. The rate of
positivity of anti-HEV IgG in pregnant women with low level
of education was 11.4% whereas 3% in university educated
women. There was a significant difference between
seropositivity of anti-HEV IgG and the trimester of pregnancy.
The most of anti-HEV IgG positive were occurred in the third
trimester of pregnancy (8.6%).Out of this 22 anti-HEV IgG
positive cases 4.4% were living in urban and 6.3% were in rural
areas.
Conclusion: The present results showed that there is a direct
relation between age, lower levels of education and trimester of
pregnancy with the seroprevalence of HEV.
