اثر هيپوكسي تناوبي بر شاخص هاي عملكرد ريوي در افراد چاق مبتلا به ديابت نوع دو

the EffeThe Effects of Intermittent Hypoxiaon Pulmonary Function Indicesin Obese Patientswith Type Didiabetes

مقدمه: افراد چاق به دليل داشتن چربي بيشتر در بالاتنه و فشاري كه بر سيستم تنفسي آن ها وارد مي شود، دچار مشكلات تنفسي و كاهش شاخص هاي عملكردي ريه مي شوند. هدف ما از اين پژوهش بررسي اثر 15 روز هايپوكسي تناوبي بر شاخص هاي عملكردي ريوي در بيماران چاق مبتلا به ديابت نوع دو بوده است.

Introduction: Obese peoplewill beaffected by respiratory problems and impaired pulmonary function parameters because ofmore fatin thetrunk andmore pressure on the respiratory system. The aim of this study was to evaluatethe effects of 15 days of intermittent hypoxia on pulmonary functiontest inobese patient with type 2 diabetes. Materials and Methods: 7 obese subjects(1man,6women) with type II diabetes, with mean BMI of 32.42 plusmn 1.06 and the age range of 5070 years, volunteered to participate inthestudy. The intervention consisted of 15 sessions of intermittent hypoxia, one hour per day, for fifteen consecutive days.pulmonaryfunction parameters including: VC, FVC, FEV1,TV, PEF, FEF2575%, MVV and BMI and VO2max in pre and posttests were measured. Findings: After 15 days of intermittenthypoxia VC, TV, FEV1, MVV, FVC, FEF 2575% were not changed significantly.However, PEF and VO2max had significant increases of 6.5% and 13%, respectively(p<0.05), furthermore BMI had a nonsignificant decrease of 3.5%. Discussion Conclusion: Findingsofthis studyindicate that despite positive effects of intermittent hypoxiaonVO2max and PEF,BMI and other pulmonary parameters not significantly change after 15 consecutive sessions of intermitent hypoxic exposure.