در بيماران قلبي و عروقي با انسداد رگي و مقايسه آن با گروه كنترل )HDL2 ,HDL3( و زير گروههاي آن HDL VLDL ، LDL بررسي ميزان كلسترول ، تري گليسيريد،

Determination of Total Cholesterol, Triglyceride, LDL-C, VLDL-C, HDL-C and HDL Subfractions in Coronary Heart Disease

The present research was carried out on 99 males and females. The sample was consisted of individuals between 33 to 75 years of age. fifty-seven of them had CAD and 42 without CAD. Biochemical tests were performed to measure TC, TAG, HDL-C, HDL2-C and LDL-C. Precipitation method was used to measure HDL2-C. The average amount of TC, TAG, LDL-C and the TC/HDL-C and LDL-C/HDL-C ratio increased significantly in CAD patients compared to normal individuals. On the other hand the average amount of HDL-C, HDL2-C and LDLD-C/HDL-C ratio decreased significantly in comparison with the control groups. About 68% of patients had a cholestrol level above the normal and 22% of them showed low levels of HDL-C while 96% of them represented low levels of HDL2-C. These indicate the value and importance of HDL2-C measurement in the process of diagnosis. The precipitation method apparently was the best, and is suggested to be used as a routine test in clinical diagnostic laboratories. Also it was found out that the determination of HDL20-C /HDL3-C and TC/HDL-C is the third important factor in diagnosis. In addition, considering the significant differences in the amounts of TAG and VLDL in patients compared to normal individuals, studying these factors should also be taken into consideration.