غربالگري نارسايي مزمن كليوي در شهروندان استان تهران

Epidemiology of Chronic Renal Failure in Tehran-Iran

Chronic renal failure (CRF) is a devastating medical and social problem which remains asymptomatic up to end-stage renal disease (ESRD). Implementation of a policy to screen these patients is of great value in developing countries where renal replacement therapy is simply not available to the vast population. As the first step, we conducted this mass screening study to define the epidemiology of CRF among citizens of Tehran. A total number of 4832 residents were randomly selected. Serum creatinine level was tested. The subjects with high creatinine level (male: > 1..5mg/dl, female: > 1.2mg/dl) were invited and confirmatory investigations including complete 24hr urine analysis, serum biochemistry tests and renal-urinary tract ultrasonography were carried out. Serum creatinine levels were high in 222 subjects. Following confirmatory evaluations, CRF was diagnosed in 10 patients as well as ESRD in one patient). CRF patients consisted of 6 males and 4 females with a average age of 53.5 years. Three of them had no underlying disease. Three patients were diabetic. Two patients suffered from hypertension as, and one patient had a history of frequent kidney stones. This study defined the prevalence of CRF in Tehran for the first time which was much more than expected.