كليدواژه :
Monitoring , اختلالات اسيد و باز , بيهوشي عمومي , عمل جراحي , پايش , Acid-base Disturbances , گازهاي خون شرياني , General Anesthesia , پزشكي , Operation , Blood Gases
چكيده لاتين :
The life of living organisms is dependent upon the maintenance of an acid-base equilibrium. In patients undergoing surgery, acid-base imbalance during general anesthesia causes disruption in function of cardiovascular, respiratory, musculoskeletal and the central nervous system. In this study, acid-base disruption and its effects during general anesthesia was studied in 60 patients. The patients were divided in to three groups based on the site of surgery: abdominal(I), extremities (II) and head & neck (III). Core temperature, type, and volume of injected fluids and bicarbonate were recorded. In the second, third, and fourth hours of surgery, arterial blood gases and pH were measured. The incidence and degree of metabolic acidosis in all patients was significantly related to the duration of the surgery (P<0.05). The number of acidotic patients and the number of patients that required treatment were also greater in groups I and II than in group III (P<0.05). Although all patients were hypothermic throughout the surgery, there was no significant relationship with development of acidosis. No relationship was found between the type and volume of solution adminstered (normal saline, ringer, or combinations) and development of acidosis. In our opinion monitoring of acid-base status in prolonged surgery especially in abdominal and extremity operations is necessary.