اپيدميولوژي تظاهرات باليني و آزمايشگاهي بيماران بستري مبتلا به وبا و گزارش تظاهرات ناشايع آن طي همه گيري سال 1377 در شهر گرگان

Gastro-enteritis due to vibrio cholera were increased suddenly in summer of 1998 in our country. In this research we studied epidemiological and clinical features of cholerae patients. vibrio cholera isolated , from 189 (3.3%) patients from 5611 stool samples. 182 (96.2%) vibrio cholera O1 isolated. 46 (24%) patients with positive stool cultures for vibrio cholera were hospitalized. 50% patients were 15-45 yrs. No sex predominency was seen. The important observations in this study including : fever in 28.1% (13) o f patients, sever leukocytosis in 15% (7) of patients, RBC in stool in 33% (15) of patients. Fever and neutrophilia and RBC in stool probably shows co-infection with other intestinal pathogens or different semtypes of vibrio cholera with new characterestics. So we are recommending extensive research to be done on serotyping of all of the isolates of vibrio cholera and other intestinal pathogens simultaneousely.