سرواپيدميولوژي آنتي بادي هاي ضدتوكسوپلاسما در زنان مراجعه كننده براي مشاوره ازدواج

The prevalency of toxoplasma antibodies in women during marriage consultation in Gorgan

Toxoplasmosis is a disease caused by a ubiquitous, obligate intra cellular protozoan "toxoplasma gondii". Based on serological evidences, toxoplasmosis infection is a widespread disease with regard to this fact and because to the occurence of congenital toxoplasmosis infections due to asymptomatic infections in pregnant women, determination of the rate of toxoplasma antibodies (IgG, IgM) before pregnancy and finding the involved factors in increasing toxoplasmosis prevalence seems to be necessary. This study was a cross sectional and discriptive study and sample population was the women referred for marriage consultation the prevalence of toxoplasma antibodies (IgG, IgM) was determined by ELISA method. Blood samples were collected randomly from 300 women referred to the center for consultation in 2001 and they was transferred to the Laboratory for antibodies determination. The results showed that the general prevalence to the positive cases based on high titer of LgG was 48.3% and of IgM was 11.7%. There was not any relation between positive cases and age, education, place of residence, job, keeping domestic animals (except cat) vegetable consumption and wash-up, but there was a relation between the positive cases of IgM and keeping cat at home (PV 5 0.025). More over 51.7% of pregnant women in Gorgan were seronegative and the were prone to acute toxoplasmosis during their pregnancy. The results of this study confirm that the determination of the diagnostic toxopalsmosis is an necessary test during pregnancy.