پديد آورندگان :
Ghavam, Ramak Colorectal Research Center- Rasoul-e-Akram Hospital -Iran University of Medical Sciences -Tehran , Mokhtare, Marjan Colorectal Research Center- Rasoul-e-Akram Hospital -Iran University of Medical Sciences -Tehran , Zare-mirzaie, Ali Department of Pathology - Rasoul-e-Akram Hospital - Iran University of Medical Sciences - Tehran , Aziz Ahari, Alireza Department of Radiology - Rasoul-e-Akram Hospital - Iran University of Medical Sciences - Tehran , Faghihi, Amirhosein Colorectal Research Center- Rasoul-e-Akram Hospital -Iran University of Medical Sciences -Tehran , Hejrati, Alireza Department of Internal Medicine - Rasoul-e-Akram Hospital - Iran University of Medical Sciences - Tehran
چكيده فارسي :
A 48-year-old man was found to have elevated liver enzymes and clinical manifestations of icter، itching، nausea، and vomiting. He had developed a severe hepatotoxic reaction، liver fibrosis، and cirrhosis after treatment with acitretin 25 mg daily (oral retinoid، which is the derivative of etretinate). Elevated serum aminotransferase levels، which are usually reversible، have been reported during treatment with acitretin، however; the present study indicates a warning message that severe hepatotoxic injury may follow such a treatment.
