Regioselective Bromination and Subsequent Suzuki Cross-Coupling of Highly Electron Deficient 5,10,15,20-Tetrakis(trifluoromethyl)porphyrin

5,10,15,20-Tetrakis(trifluoromethyl)porphyrin zinc complex 2 has been shown to undergo monobromination and regioselective dibromination to give β-bromoporphyrins 3a–c. The free base β-bromoporphyrins 4a,b are converted to aryl porphyrins through Suzuki cross-coupling reaction.