Title of article :
A novel synthesis of tricyclo[5.1.0.03,5]octane-2,6-dione derivatives via double Michael addition-induced cyclopropanation reactions
Author/Authors :
Sadao Tsuboi، نويسنده , , Zhong-Xuan Ye، نويسنده , , Katsushi Kunito، نويسنده , , Takashige Ono، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Pages :
10
From page :
3035
To page :
3044
Abstract :
Tricyclo[5.1.0.03,5]octane-2,6-diones 1a–q were prepared in moderate yields by the reaction of α,β-unsaturated esters 2 with dihalomethane in the presence of butyllithium, and by the reaction of dichloromethyl α,β-unsaturated ketones 3 with sodium ethoxide, respectively. This reaction was newly explained by a mechanism involving intermolecular double Michael additions of enolate anion 4 of ketones 3 and the following cyclopropanation.
Keywords :
6-dione , Tandem reaction , Cyclopropanation , Michael addition , 5]octane-2
Journal title :
Tetrahedron
Serial Year :
2001
Journal title :
Tetrahedron
Record number :
1081886
Link To Document :
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