Author/Authors :
Jaime A Valderrama، نويسنده , , David Pessoa-Mahana، نويسنده , , Ricardo A Tapia، نويسنده , , Antonieta Rojas de Arias، نويسنده , , Héctor Nakayama، نويسنده , , Susana Torres، نويسنده , , Jorge Miret، نويسنده , , Mar??a Elena Ferreira، نويسنده ,
Abstract :
Styrene reacts with highly electrophilic monosubstituted 1,4-benzoquinones to provide pyranobenzoquinone and phenanthrene derivatives, depending on the nature of the quinone substituent. The participation of transient Diels–Alder adduct intermediates in these reactions and their thermal-induced rearrangements are discussed. The in vitro antiparasital effects of the pyranobenzoquinones against Trypanosoma cruzi and Leishmania spp. are reported.
