Author/Authors :
Nicole M.A.J Kriek، نويسنده , , Dmitri V. Filippov، نويسنده , , Hans van den Elst، نويسنده , , Nico J. Meeuwenoord، نويسنده , , Godefridus I. Tesser، نويسنده , , Jacques H. van Boom، نويسنده , , Gijs A. van der Marel، نويسنده ,
Abstract :
The uridylylated amino acid building blocks 2-cyanoethyl-(Nα-9-fluorenylmethoxy-carbonyl-tyrosin-4-yl)-(2′,3′-di-O-acetyluridin-5′-yl) phosphate and 2-chlorophenyl-(Nα-fluorenyl-methoxycarbonyl-serin-3-yl)-(2′,3′-di-O-acetyluridin-5′-yl) phosphate have been used successfully in an on-line SPPS of the VPgpU from the polio, coxsackie and cowpea mosaic virus.
Keywords :
Rink Amide resin , genome-linked peptides , solid phase peptide synthesis , uridylylated amino acid building blocks