Title of article :
Synthesis of an external beta-turn based on the GLDV motif of cell adhesion proteins
Author/Authors :
David E. Davies، نويسنده , , Paul M. Doyle، نويسنده , , Richard D. Hill، نويسنده , , Douglas W. Young، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
The (3S,6S,10S)-7/5 bicyclic lactam , designed as an external turn constraint, was synthesised by a new stereoselective route involving Eschenmoser condensation. The cyclic peptide containing the integrin recognition motif GLDV added across the amino and carboxyl groups of the lactam external constraint was prepared.
Keywords :
Integrin , Eschenmoser olefination , bicyclic lactam
Journal title :
Tetrahedron
Journal title :
Tetrahedron