Author/Authors :
Daqing Shi، نويسنده , , Guo-Lan Dou، نويسنده , , Zhengyi Li، نويسنده , , Sai-Nan Ni، نويسنده , , Xiaoyue Li، نويسنده , , Xiang-Shan Wang، نويسنده , , Hui Wu، نويسنده , , Shun-Jun Ji، نويسنده ,
Abstract :
A facile synthetic method using low-valent titanium reagent (TiCl4/Zn system) to promote the novel reductive cyclization of 2-nitrobenzamides and triphosgene is described. Sequentially, a series of quinazoline-2,4-diones were synthesized in good yields.
Keywords :
Quinazolin-2 , 4-dione , Low-valent titanium reagent , Synthesis