Author/Authors :
Joachim Horn، نويسنده , , Ho Yin Li، نويسنده , , Stephen P. Marsden، نويسنده , , Adam Nelson، نويسنده , , Rachel J. Shearer، نويسنده , , Amanda J. Campbell، نويسنده , , David House، نويسنده , , Gordon G. Weingarten، نويسنده ,
Abstract :
An efficient and convergent one-step synthesis of substituted dihydroquinolin-2-ones from α,β-unsaturated esters and aminoaryl pinacolboronates under rhodium catalysis is reported. The reaction is easily applicable in parallel synthesis format and provides convenient access to this pharmaceutically-relevant motif.
