Title of article
Tandem cross-Rauhut–Currier/cyclization reactions of activated alkenes to give densely functionalized 3,4-dihydropyrans
Author/Authors
Wen Liu، نويسنده , , Jing Zhou، نويسنده , , Changwu Zheng، نويسنده , , Xingkuan Chen، نويسنده , , Hua Xiao، نويسنده , , Yingquan Yang، نويسنده , , Yinlong Guo، نويسنده , , Gang Zhao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
6
From page
1768
To page
1773
Abstract
A novel tandem cross-Rauhut–Currier/cyclization reaction between α,β-unsaturated ketones was developed. Using DABCO (20 mol %) as the catalyst, a series of densely functionalized 3,4-dihydropyrans were obtained in excellent yields and stereoselectivities (up to 98% yield, >99:1 dr). A tentative catalytic cycle was proposed with key intermediates confirmed by ESIMS studies.
Keywords
Rauhut–Currier reaction , Activated alkenes , cyclization reaction , 3 , 4-Dihydropyrans
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103003
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