Title of article :
A novel method for the synthesis of 3-fluoro-4-aryl-2-pyridone via unprecedented denitration
Author/Authors :
Xiao-Wei Wang، نويسنده , , Hai-Feng Cui، نويسنده , , Haifeng Wang ، نويسنده , , Ying-Quan Yang، نويسنده , , Gang Zhao، نويسنده , , Shizheng Zhu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A simple and novel method to the synthesis of 3-fluoro-4-aryl-2-pyridone from a Michael-adduct of fluoronitroacetate and α,β-unsaturated ketone is reported. With (NH4)2CO3 as the N-source and TsOH as the promoted acid, a series of fluorinated-pyridones was obtained with moderate to good yields.
Keywords :
Cyclization , denitration , Fluorine-containing 2-pyridone , ? , ?-Unsaturated ketone
Journal title :
Tetrahedron
Journal title :
Tetrahedron
