Title of article :
Molecular-Iodine-Catalyzed One-Pot Synthesis of 1,5-Benzodiazepine Derivatives under Solvent-Free Conditions
Author/Authors :
Lu، Jun نويسنده , , Chen، Wei-Yi نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
-1336
From page :
1337
To page :
0
Abstract :
2,3-Dihydro-1H-1,5-benzodiazepines have been synthesized from ophenylenediamine (OPDA) and ketones under solvent-free conditions in the presence of a catalytic amount of molecular iodine. All of the ketones, including cyclic ketones and acyclic ketones, reacted smoothly with OPDA to furnish products. Compared to other reaction conditions, this new protocol has the advantage of excellent yield and short reaction time at room temperature.
Keywords :
ketones , benzodiazepine , o-Phenylenediamine , iodine , solvent-free
Journal title :
Synlett
Serial Year :
2005
Journal title :
Synlett
Record number :
110453
Link To Document :
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