Title of article :
Mechanism-Based Neddylation Inhibitor
Author/Authors :
Matthew D. Petroski، نويسنده ,
Issue Information :
ماهنامه با شماره پیاپی سال 2010
Abstract :
elucidate the mechanism of action of MLN4924, a NEDD8-activating enzyme inhibitor. MLN4924 requires the activity of the enzyme to generate a NEDD8-adenylate analog that potently and selectively shuts down this posttranslational modification system.
Journal title :
Chemistry and Biology
Journal title :
Chemistry and Biology
