Title of article :
Vocal Fold Surface Hydration: A Review
Author/Authors :
Ciara Leydon، نويسنده , , Mahalakshmi Sivasankar، نويسنده , , Danielle Lodewyck Falciglia، نويسنده , , Christopher Atkins، نويسنده , , Kimberly V. Fisher، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Pages :
8
From page :
658
To page :
665
Abstract :
Vocal fold surface liquid homeostasis contributes to optimal vocal physiology. In this paper we review emerging evidence that vocal fold surface liquid is maintained in part by salt and water fluxes across the epithelium. Based on recent immunolocalization and electrophysiological findings, we describe a transcellular pathway as one mechanism for regulating superficial vocal fold hydration. We propose that the pathway includes the sodium–potassium pump, sodium–potassium–chloride cotransporter, epithelial sodium channels, cystic fibrosis transmembrane regulator chloride channels, and aquaporin water channels. By integrating knowledge of the regulating mechanisms underlying ion and fluid transport with observations from hydration challenges and treatments using in vitro and in vivo studies, we provide a theoretical basis for understanding how environmental and behavioral challenges and clinical interventions may modify vocal fold surface liquid composition. We present converging evidence that clinical protocols directed at facilitating vocal fold epithelial ion and fluid transport may benefit healthy speakers, those with voice disorders, and those at risk for voice disorders.
Keywords :
Bioelectric parameters , Surface hydration , vocal folds , Epithelia , Immunolocalization
Journal title :
Journal of Voice
Serial Year :
2009
Journal title :
Journal of Voice
Record number :
1280538
Link To Document :
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