Title of article :
Maternal high-fat intake during pregnancy programs metabolic-syndrome-related phenotypes through liver mitochondrial DNA copy number and transcriptional activity of liver PPARGC1A
Author/Authors :
Adriana Laura Burgue?o، نويسنده , , Romina Cabrerizo، نويسنده , , Noelia Gonzales Mansilla، نويسنده , , Silvia Sookoian، نويسنده , , Carlos Jose Pirola، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Abstract :
In this study, we contrasted the hypothesis that maternal diet during pregnancy has an impact on fetal metabolic programming through changes in liver mitochondrial DNA (mtDNA) content and transcriptional activity of Ppargc1a and that these effects are sex specific.
Keywords :
Mitochondrial DNA , PGC1a , Ppargc1a , Mitochondrial copy number , NAFLD , Liver , Insulin resistance , gene expression , Insulin resistance , Metabolic programming , High-fat diet
Journal title :
The Journal of Nutritional Biochemistry
Journal title :
The Journal of Nutritional Biochemistry
