Title of article :
Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles Original Research Article
Author/Authors :
Damien Cressier، نويسنده , , Caroline Prouillac، نويسنده , , Pierre Hernandez، نويسنده , , Christine Amourette، نويسنده , , Michel Diserbo، نويسنده , , Claude Lion، نويسنده , , Ghassoub Rima، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Abstract :
In this work, we report the synthesis and characterization of new compounds derived from benzothiazoles and thiadiazoles. We observed that structural modifications on these skeletons affected the antioxidant activity. Thiol and aminothiol compounds derived from thiadiazoles and benzothiazoles showed an interesting antioxidant property. The radioprotective activity has also been evaluated in mice. Some of these compounds could be good radioprotectors.
Keywords :
Radioprotection , Phosphorothioates , Thiosulfonic acid , Benzothiazole , Thiadiazole , antioxidant
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry