Synthesis and reaction of secondary and primary diorganozinc reagents using a boron–zinc exchange reaction: A useful method for the stereo- and regioselective formation of new carboncarbon bonds

Applications of the boron–zinc exchange reaction to make new carboncarbon bonds are reviewed. Functionalized chiral secondary alkylzinc reagents can be prepared by this exchange reaction and allows to perform formal enantioselective Michael-additions with umpolung of reactivity. The scope of substrate controlled diastereoselective hydroborations can be considerably enhanced by this methodology. A chemoselective approach to difunctionalized arylsilanes is also described.