Title of article :
Statistical analysis of DNT detection using chemically functionalized microcantilever arrays
Author/Authors :
Bosco، نويسنده , , F.G. and Bache، نويسنده , , Arnold M. and Hwu، نويسنده , , E.-T. and Chen، نويسنده , , C.H. and Andersen، نويسنده , , S.S. and Nielsen، نويسنده , , K.A. and Keller، نويسنده , , S.S. and Jeppesen، نويسنده , , J.O. and Hwang، نويسنده , , I.-S. and Boisen، نويسنده , , A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Pages :
6
From page :
1054
To page :
1059
Abstract :
The need for miniaturized and sensitive sensors for explosives detection is increasing in areas such as security and demining. Micrometer sized cantilevers are often used for label-free detection, and have previously been reported to be able to detect explosives. However, only a few measurements from 1 to 2 cantilevers have been reported, without any information on repeatability and reliability of the presented data. In explosive detection high reliability is needed and thus a statistical measurement approach needs to be developed and implemented. We have developed a DVD-based read-out system capable of generating large sets of cantilever data for vapor and liquid phase detection of 2,4-dinitrotoluene (DNT). Gold coated cantilevers are initially functionalized with tetraTTF-calix[4]pyrrole molecules, specifically designed to bind nitro-aromatic compounds. The selective binding of DNT molecules on the chemically treated surfaces results in significant bending of the cantilevers and in a decrease of their resonant frequencies. We present averaged measurements obtained from up to 72 cantilevers being simultaneously exposed to the same sample. Compared to integrated reference cantilevers with non-selective coatings the tetraTTF-calix[4]pyrrole functionalized cantilevers reveal a uniform and reproducible behavior.
Keywords :
Explosives detection , DVD-ROM , Cantilever sensor , Optical read-out , tetrathiafulvalene
Journal title :
Sensors and Actuators B: Chemical
Serial Year :
2012
Journal title :
Sensors and Actuators B: Chemical
Record number :
1440922
Link To Document :
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