Author/Authors :
ءlvarez، نويسنده , , Mercedes and Fernلndez-Lanas، نويسنده , , David and Joule، نويسنده , , John A، نويسنده ,
Abstract :
A synthesis of deoxyvariolin B (5) is described. The tricyclic pyridopyrrolopyrimidone (11) was prepared from 7-azaindole via lithiation at C-2, introduction of an aminoethyl side-chain, then closure of the third ring. A heteroaryl palladium(0)-catalysed coupling reaction was used to introduce a pyrimidine substituent at C-5.
