Author/Authors :
Liu، نويسنده , , Wenming and Xu، نويسنده , , David D and Repi?، نويسنده , , Oljan and Blacklock، نويسنده , , Thomas J، نويسنده ,
Abstract :
A mild and general method for lactone aminolysis is reported. Sodium 2-ethylhexanoate (NaEH) is found to serve both as a base and a catalyst in aminolysis of a variety of lactones by benzylamine hydrochloride. The nearly neutral pH conditions make this method applicable to many acid/base sensitive substrates.
